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95 Rue du Faubourg Saint-Antoine
75011 PARIS
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0186953095

Bastille, Ledru-Rollin, Gare de Lyon. ✅ Bilan de la vue ➡ ⌚ Rendez-vous ophtalmo ✆ 01 86 95 30 95★★★★★ ✅ Ophtalmologue spécialiste des uvéites, de la rétine et de la DMLA ✅ RDV Rapide ➡ Paris 11 + ♿Accès PMR

News

Guidance on Noncorticosteroid Systemic Immunomodulatory Therapy in Noninfectious Uveitis

Sawsen Salah-Berly

Nouvel article publié dans l'American Journal of Ophthalmology sur la prise en charge des uvéites non-infectieuses.

An international, expert-led consensus initiative to develop systematic, evidence-based recommendations for the treatment of noninfectious uveitis in the era of biologics. Clinical Relevance: The availability of biologic agents for the treatment of human eye disease has altered practice patterns for the management of noninfectious uveitis. Current guidelines are insufficient to assure optimal use of noncorticosteroid systemic immunomodulatory agents.

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ROCK-1 mediates diabetes-induced retinal pigment epithelial and endothelial cell blebbing: Contribution to diabetic retinopathy.

Sawsen Salah-Berly

In diabetic retinopathy, the exact mechanisms leading to retinal capillary closure and to retinal barriers breakdown remain imperfectly understood. Rho-associated kinase (ROCK), an effector of the small GTPase Rho, involved in cytoskeleton dynamic regulation and cell polarity is activated by hyperglycemia. In one year-old Goto Kakizaki (GK) type 2 diabetic rats retina, ROCK-1 activation was assessed by its cellular distribution and by phosphorylation of its substrates, MYPT1 and MLC.

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